Clinical Care Practices Shape Microbiome-Associated Bloodstream Infection Risk in Geographically Distinct NICUs
Our findings demonstrate that modifiable clinical care practices shape the developing microbiome of preterm infants and contribute to geographic differences in BSI epidemiology. The skin microbiome represents a potentially significant risk factor for invasive infection. Further work to clarify how specific clinical practices influence pathogen colonization may inform strategies to reduce BSI incidence in preterm infants.
Authors
- Jiajun Zhu (ORCID: https://orcid.org/0000-0003-2357-267X)
- Henry T. Akinbi (ORCID: https://orcid.org/0000-0003-2852-5856)
- Zheng Shen (ORCID: https://orcid.org/0000-0003-2365-2602)
- Lizhong Du
- Liping Shi
- David B. Haslam
- Yanping Xu
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Children's Hospital of Zhejiang University (CN)
- Perinatal Institute (GB)
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- University of Cincinnati (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1093/cid/ciag213
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00