Endothelial tPA-dependent recruitment of microglia to vessels protects the blood-brain barrier after stroke
Collectively, these findings indicate that endothelial tPA promotes microglial recruitment to blood vessels and plays a protective role in preserving BBB integrity after ischemic stroke.
Authors
- Eloïse Lemarchand (ORCID: https://orcid.org/0000-0001-6781-0444)
- Benoit D. Roussel (ORCID: https://orcid.org/0000-0003-0575-8112)
- Tamara Etuzé
- Louis Fosset
- Denis Vivien
Institutions
- Inserm (FR)
- Normandie Université (FR)
- Centre Hospitalier Universitaire de Caen Normandie (FR)
- Cyceron (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1186/s12987-026-00801-w
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00