Paternal snus use in puberty and increased risk for asthma and allergies in offspring: a RHINE/RHINESSA two-generation study
Paternal snus use starting in puberty was associated with a higher risk of asthma and other respiratory and allergic symptoms in offspring. These findings support the hypothesis that exposures in puberty may impact future generations' respiratory health, possibly through epigenetic changes. This highlights the need for research on exposures during this period and actions to prevent habits that could negatively impact future offspring's health.
Authors
- Elin Helga Thorarinsdottir (ORCID: https://orcid.org/0000-0001-6561-3746)
- Nils Oskar Jõgi (ORCID: https://orcid.org/0000-0002-9600-1950)
- Valentina Lando (ORCID: https://orcid.org/0009-0003-6794-046X)
- A Oudin
- S Accordini
- M Holm (ORCID: https://orcid.org/0000-0002-9327-5139)
- Juan Pablo López-Cervantes (ORCID: https://orcid.org/0000-0002-4668-911X)
- Francisco Javier Callejas-González
- Vivi Schlünssen
- Ane Johannessen
- Cecilie Svanes
- Lars Modig
- Shyamali C Dharmage
- Randi J Bertelsen
- Andrei Malinovschi
- Christer Janson
Institutions
- University of Verona (IT)
- Reykjavík University (IS)
- Uppsala University (SE)
- National Academy of Medicine (US)
- Uppsala University Hospital (SE)
- University of Iceland (IS)
- The University of Melbourne (AU)
- Haukeland University Hospital (NO)
- Danish Ramazzini Center (DK)
- Department of Medical Sciences (RU)
- Hospital General Universitario de Albacete (ES)
- Complejo Hospitalario Universitario de Albacete (ES)
- University of Bergen (NO)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- International Journal of Epidemiology
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1093/ije/dyag035
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00