Combined impact of ROR2 and its ligands on the pathogenesis and prognosis of idiopathic pulmonary fibrosis.

ROR2 levels in BAL fluid are independently associated with IPF pathogenesis and prognosis, and may serve as a useful biomarker for identifying molecular endotypes and assessing clinical risk. Exploratory findings suggest that ROR2 and its ligand may modulate prognosis in a subset of patients.

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Publication Details

Journal
PubMed
Published
2026-03-27
DOI
https://doi.org/10.36141/svdld.2026.17921
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Combined impact of ROR2 and its ligands on the pathogenesis and prognosis of idiopathic pulmonary fibrosis.

Seung-lee Park, Jae‐Joong Kim, C. H. Park, Jongin Lee et al.
PubMed
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Combined impact of ROR2 and its ligands on the pathogenesis and prognosis of idiopathic pulmonary fibrosis.

Seung-lee Park, Jae‐Joong Kim, C. H. Park, Jongin Lee, Myung-Shin Kim, Hun Soo Chang, Min Kyung Kim, Hun Gyu Hwang, Eunjeong Seo
article en

Abstract

ROR2 levels in BAL fluid are independently associated with IPF pathogenesis and prognosis, and may serve as a useful biomarker for identifying molecular endotypes and assessing clinical risk. Exploratory findings suggest that ROR2 and its ligand may modulate prognosis in a subset of patients.

PubMedVol. 43(1)
Soonchunhyang University (KR), Soonchunhyang University Hospital Seoul (KR), Bucheon University (KR)
Good health and well-being
Openalex Percentile: Top 3%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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