Bibliometric Analysis On Non-Invasive Prenatal Testing

Aim: The study aimed to analyze and assess theglobal research development, collaborative network,prestigious literature and tendency of themes aboutNon-invasive prenatal testing(SDisease) (NIPT).Material and Method: A total of 1639 scientificpublications between the years 2011-2025 wereexamined in this study from the Web Science (WoS)database databases. Country and institutionalcollaborations, co-citation networks, and keywordcollocations were visualized for the data analysis inVOSviewer.Results: The publications in the area of NIPT were foundto have increased over years. The PR China ranked the firstboth in terms of publications (n=384), with United Statesof America and United Kingdom being the countrieswith most significant international collaborationnetworks included respectively (n=206) and (n=199). Thejournal Prenatal Diagnosis contributed most, with 171publications and 4,243 citations. Results Analysis of theKeywords showed that research interest has shifted fromsimple aneuploidy screening to technical (fetal fraction,mosaicism and next-generation sequencing) as well associal aspects (genetic counseling and ethical issues).Conclusion: The NIPT field is a very active and maturearea of research with an increasing volume of interest.The People’s Republic of China is the largest volumecontributor, US and UK are in the hub of internationalcollaboration and scientific influence. The emphasisin the field has changed from pure screening to morechallenging issues like fetal fraction, mosaicism, geneticcounseling and ethics.