A critical review of midazolam 10 mg autoinjector for the treatment of convulsive status epilepticus in adults

The midazolam autoinjector offers a meaningful advance in the treatment of status epilepticus by enabling rapid, consistent intramuscular delivery without preparation. Its design directly addresses the practical limitations of existing therapies and is likely to encourage adoption in prehospital and other time-critical settings. As emergency care increasingly prioritizes early intervention, autoinjector-based benzodiazepines are poised to play an expanding role in modern seizure-rescue strategies.

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Publication Details

Journal
Expert Review of Neurotherapeutics
Published
2026-03-28
DOI
https://doi.org/10.1080/14737175.2026.2652300
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A critical review of midazolam 10 mg autoinjector for the treatment of convulsive status epilepticus in adults

Francesco Brigo, Simona Lattanzi
Expert Review of Neurotherapeutics
Epilepsy research and treatment
article

A critical review of midazolam 10 mg autoinjector for the treatment of convulsive status epilepticus in adults

Francesco Brigo, Simona Lattanzi
article en

Abstract

The midazolam autoinjector offers a meaningful advance in the treatment of status epilepticus by enabling rapid, consistent intramuscular delivery without preparation. Its design directly addresses the practical limitations of existing therapies and is likely to encourage adoption in prehospital and other time-critical settings. As emergency care increasingly prioritizes early intervention, autoinjector-based benzodiazepines are poised to play an expanding role in modern seizure-rescue strategies.

Expert Review of Neurotherapeutics
Marche Polytechnic University (IT), Azienda Sanitaria di Firenze (IT)
Good health and well-being
Openalex Percentile: Top 9%
Epilepsy research and treatment
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