Patterns of Thyroid-Stimulating Hormone Test After GLP-1 RAs Initiation in Patients on Levothyroxine: A Trial Emulation Study
TSH testing patterns did not differ between GLP-1 RAs and SGLT-2is, despite the greater likelihood of requiring levothyroxine dose adjustment associated with weight loss seen with GLP-1 RAs therapy. Given levothyroxine's widespread use, this gap suggests missed opportunities for timely and weight-responsive thyroid monitoring.
Authors
- TIANZE JIAO
- Rozalina Grubina McCoy (ORCID: https://orcid.org/0000-0002-2289-3183)
- Fanxing Du
- Juan Pablo Brito (ORCID: https://orcid.org/0000-0003-1840-1745)
- Hui Shao
- Yishan Chen (ORCID: https://orcid.org/0009-0001-5474-5900)
- Qing Liu
- Naykky M Singh Ospina
Institutions
- University of Maryland, Baltimore (US)
- Center for Drug Evaluation and Research (US)
- Emory University (US)
- Diabetes Australia (AU)
- University of Florida (US)
- Woodruff Health Sciences Center (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- Florida College (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1210/clinem/dgag131
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00