Cover Feature: Acyl Phosphate‐Driven Acylation in Biology, Chemistry, and in Between

This landscape illustrates acyl phosphates as “highest energy” acyl donor in biological acylations. The review by Lenard Saile and Charalampos G. Pappas (DOI: 10.1002/anov.70019) provides an overview of their potential in chemical biology, systems chemistry, and prebiotic research. It highlights how supramolecular organization can be coupled to acyl transfer reactions to develop new roles for phosphates outside of biology. The illustration was partially created with BioRender.