Cost-effectiveness of DPYD genotyping prior to capecitabine administration for metastatic breast cancer

Our findings support the implementation of DPYD genotyping prior to capecitabine initiation in metastatic breast cancer patients. This strategy exemplifies the value of personalized medicine and pharmacogenomics in improving treatment safety and effectiveness. As sequencing technologies advance and become affordable, integration of genotyping into routine oncology care is increasingly feasible.

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Publication Details

Journal
Breast Cancer Research and Treatment
Published
2026-03-28
DOI
https://doi.org/10.1007/s10549-026-07948-y
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost-effectiveness of DPYD genotyping prior to capecitabine administration for metastatic breast cancer

Anne Hudson Blaes, Tanvi Chiddarwar, KM Kuntz
Breast Cancer Research and Treatment
Cancer Treatment and Pharmacology
article

Cost-effectiveness of DPYD genotyping prior to capecitabine administration for metastatic breast cancer

Anne Hudson Blaes, Tanvi Chiddarwar, KM Kuntz
article en

Abstract

Our findings support the implementation of DPYD genotyping prior to capecitabine initiation in metastatic breast cancer patients. This strategy exemplifies the value of personalized medicine and pharmacogenomics in improving treatment safety and effectiveness. As sequencing technologies advance and become affordable, integration of genotyping into routine oncology care is increasingly feasible.

Breast Cancer Research and TreatmentVol. 217(1)
University of Minnesota (US)
Good health and well-being
Openalex Percentile: Top 4%
Cancer Treatment and Pharmacology
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