Associations of corticosteroid therapy with weight change and appetite in patients with advanced pancreatic cancer – a post hoc analysis from the MISTRAL trial

In long-term follow-up, corticosteroid treatment was associated with greater weight loss and poorer appetite among patients with advanced pancreatic cancer. These findings may partly be explained by a higher symptom burden among patients receiving corticosteroids. Future prospective trials are warranted to clarify the effect of long-term corticosteroid treatment on weight and appetite.

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Publication Details

Journal
Supportive Care in Cancer
Published
2026-03-28
DOI
https://doi.org/10.1007/s00520-026-10585-2
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of corticosteroid therapy with weight change and appetite in patients with advanced pancreatic cancer – a post hoc analysis from the MISTRAL trial

Charlotte Goodrose-Flores, Stephanie E. Bonn, Kathrin Wode, Linda Björkhem-Bergman
Supportive Care in Cancer
Nutrition and Health in Aging
article

Associations of corticosteroid therapy with weight change and appetite in patients with advanced pancreatic cancer – a post hoc analysis from the MISTRAL trial

Charlotte Goodrose-Flores, Stephanie E. Bonn, Kathrin Wode, Linda Björkhem-Bergman
article en

Abstract

In long-term follow-up, corticosteroid treatment was associated with greater weight loss and poorer appetite among patients with advanced pancreatic cancer. These findings may partly be explained by a higher symptom burden among patients receiving corticosteroids. Future prospective trials are warranted to clarify the effect of long-term corticosteroid treatment on weight and appetite.

Supportive Care in CancerVol. 34(4)
Swedish Foundation for Strategic Research (SE), Karolinska Institutet (SE), Integrated Cardio Metabolic Centre (SE)
Openalex Percentile: Top 4%
Nutrition and Health in Aging
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