A comparative analysis of topological domain callers over RNA-associated interactome
We examined the core principles and assumptions behind TAD-callers over RNA interactomes. To our best knowledge, this is the first time that many TAD inference methods are adapted to infer TAD-like domains on RNAs. Our results provide valuable guidance in selecting the most suitable methods for TAD inference over RNA interactomes.
Authors
- Emre Sefer (ORCID: https://orcid.org/0000-0002-9186-0270)
- Tuna Alaygut (ORCID: https://orcid.org/0009-0009-8119-3740)
Institutions
- Özyeğin University (TR)
Publication Details
- Journal
- BMC Bioinformatics
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1186/s12859-026-06432-0
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00