Possible Deslanoside‐Induced Left Posterior Fascicular Ventricular Tachycardia: A Case Report

Cardiac glycosides, including Deslanoside, are widely used for ventricular rate control in atrial fibrillation (AF). We report a 73-year-old man with paroxysmal AF and no structural heart disease who developed left posterior fascicular ventricular tachycardia (LPFVT) shortly after intravenous Deslanoside administration. A close temporal relationship was observed between drug administration and arrhythmia onset, with a shorter latency following a second intravenous dose. These findings suggest that Deslanoside may have facilitated LPFVT. This case highlights that cardiac glycosides, while effective for rate control, may occasionally precipitate Purkinje-related ventricular tachycardia.

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Publication Details

Journal
Annals of Noninvasive Electrocardiology
Published
2026-03-28
DOI
https://doi.org/10.1111/anec.70166
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
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article

Possible Deslanoside‐Induced Left Posterior Fascicular Ventricular Tachycardia: A Case Report

Chen Yao, Zhang Wenjun
Annals of Noninvasive Electrocardiology
Cardiac electrophysiology and arrhythmias
article

Possible Deslanoside‐Induced Left Posterior Fascicular Ventricular Tachycardia: A Case Report

Chen Yao, Zhang Wenjun
article en

Abstract

Cardiac glycosides, including Deslanoside, are widely used for ventricular rate control in atrial fibrillation (AF). We report a 73-year-old man with paroxysmal AF and no structural heart disease who developed left posterior fascicular ventricular tachycardia (LPFVT) shortly after intravenous Deslanoside administration. A close temporal relationship was observed between drug administration and arrhythmia onset, with a shorter latency following a second intravenous dose. These findings suggest that Deslanoside may have facilitated LPFVT. This case highlights that cardiac glycosides, while effective for rate control, may occasionally precipitate Purkinje-related ventricular tachycardia.

Annals of Noninvasive ElectrocardiologyVol. 31(3)
Fuling Center Hospital of Chongqing (CN)
Good health and well-being
Openalex Percentile: Top 4%
Cardiac electrophysiology and arrhythmias
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