Evaluation of the MEFIER score in identifying patients at high risk of endocarditis in <i>Enterococcus faecalis</i> bacteremia
Abstract In a retrospective cohort of 549 Enterococcus faecalis bacteremia episodes, the MEFIER score showed poor rule-out performance (negative likelihood ratio of 0.69), misclassifying 60% of IE episodes as low-risk. In contrast, DENOVi score achieved a low negative likelihood ratio (0.07), misclassifying only 5% while limiting unnecessary echocardiography.
Authors
- Benoît Guéry (ORCID: https://orcid.org/0000-0002-6526-0714)
- Nicolas Fourré (ORCID: https://orcid.org/0009-0006-1660-9365)
- Lars Niclauss (ORCID: https://orcid.org/0000-0003-4453-5202)
- Virgile Zimmermann (ORCID: https://orcid.org/0009-0005-1812-0216)
- Matthaios Papadimitriou-Olivgeris
- P Monney
- Georgios Tzimas
- L Senn
- Matthias Kirsch
Institutions
- Hôpital du Valais (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1093/ofid/ofag184
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00