Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Summary Nasal epithelial cell alarmin cytokine levels are reduced in patients with severe asthma following tezepelumab. This is the first report showing nasal alarmin cytokine protein expression depletion following biologics.

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Publication Details

Journal
Clinical & Experimental Allergy
Published
2026-03-27
DOI
https://doi.org/10.1111/cea.70294
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Adil Adatia, Hazel Marriott, Paige Lacy, Subhabrata Moitra
Clinical & Experimental Allergy
Asthma and respiratory diseases
article

Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Adil Adatia, Hazel Marriott, Paige Lacy, Subhabrata Moitra
article en

Abstract

Summary Nasal epithelial cell alarmin cytokine levels are reduced in patients with severe asthma following tezepelumab. This is the first report showing nasal alarmin cytokine protein expression depletion following biologics.

Clinical & Experimental Allergy
Gujarat University (IN), University of Alberta (CA), Ahmedabad University (IN)
Openalex Percentile: Top 4%
Asthma and respiratory diseases
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