Data-Centric Foundation Models in Computational Healthcare: A Survey
The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has ignited a data-centric AI paradigm that emphasizes better data characterization, quality, and scale. In healthcare AI, obtaining and processing high-quality clinical data records has been a longstanding challenge, encompassing data quantity, annotation, patient privacy, and ethics. In this survey, we investigate a wide range of data-centric approaches in the FM era (from model pre-training to inference) towards improving the healthcare workflow. We discuss key perspectives in AI security, assessment, and alignment with human values. Finally, we offer a promising outlook on FM-based analytics to enhance patient outcomes and clinical workflows in the evolving landscape of healthcare and medicine. We provide an up-to-date list of healthcare-related foundation models and datasets at https://github.com/Yunkun-Zhang/Data-Centric-FM-Healthcare.
Authors
- Mu Zhou (ORCID: https://orcid.org/0000-0003-3533-2227)
- Shaoting Zhang (ORCID: https://orcid.org/0000-0002-8719-448X)
- D. Y. Wang (ORCID: https://orcid.org/0000-0001-8270-8448)
- Jin Gao (ORCID: https://orcid.org/0000-0002-8925-5215)
- Yunkun Zhang
- Lingfeng Zhou
- Zheling Tan
- Kexin Ding
Institutions
- Shanghai Jiao Tong University (CN)
- Rutgers Sexual and Reproductive Health and Rights (NL)
Publication Details
- Journal
- ACM Computing Surveys
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1145/3800677
- Primary Topic
- Machine Learning in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00