Liquid‐Based Cytology of <scp>SMARCA4</scp> ‐Deficient Undifferentiated Tumor: A Case Report

This case demonstrates that LBC specimens from metastatic sites can preserve diagnostic cytomorphologic features of SMARCA4-UT and highlights this rare presentation with esophageal involvement and reproducible findings across two metastatic sites. Awareness of cytologic features and potential diagnostic pitfalls is essential for timely diagnosis and appropriate ancillary testing.

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Publication Details

Journal
Diagnostic Cytopathology
Published
2026-03-27
DOI
https://doi.org/10.1002/dc.70113
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Liquid‐Based Cytology of SMARCA4 ‐Deficient Undifferentiated Tumor: A Case Report

C. R. Chu, Wen‐Ying Lee, Min‐Hui Tseng, I‐Chuang Liao
Diagnostic Cytopathology
Chromatin Remodeling and Cancer
article

Liquid‐Based Cytology of SMARCA4 ‐Deficient Undifferentiated Tumor: A Case Report

C. R. Chu, Wen‐Ying Lee, Min‐Hui Tseng, I‐Chuang Liao
article en

Abstract

This case demonstrates that LBC specimens from metastatic sites can preserve diagnostic cytomorphologic features of SMARCA4-UT and highlights this rare presentation with esophageal involvement and reproducible findings across two metastatic sites. Awareness of cytologic features and potential diagnostic pitfalls is essential for timely diagnosis and appropriate ancillary testing.

Diagnostic Cytopathology
National Sun Yat-sen University (TW), Chi Mei Medical Center (TW), National Cheng Kung University (TW)
Openalex Percentile: Top 5%
Chromatin Remodeling and Cancer
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