Short-term maternal outcomes after intraoperative administration of prophylactic oxytocin during cesarean sections: a retrospective cohort study with a comparison of different administration protocols

Very high intraoperative oxytocin doses were not associated with reduced blood loss and were frequently administered in women at increased bleeding risk, suggesting confounding by indication. These results should therefore be regarded as hypothesis-generating rather than definitive evidence to guide prophylactic dosing.

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Publication Details

Journal
Archives of Gynecology and Obstetrics
Published
2026-03-28
DOI
https://doi.org/10.1007/s00404-026-08391-6
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
0.00
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article

Short-term maternal outcomes after intraoperative administration of prophylactic oxytocin during cesarean sections: a retrospective cohort study with a comparison of different administration protocols

Anna Elisabeth Hentrich, Anne Kristina Kämpf, Vanessa Neef, Samira Catharina Hoock et al.
Archives of Gynecology and Obstetrics
Maternal and fetal healthcare
article

Short-term maternal outcomes after intraoperative administration of prophylactic oxytocin during cesarean sections: a retrospective cohort study with a comparison of different administration protocols

Anna Elisabeth Hentrich, Anne Kristina Kämpf, Vanessa Neef, Samira Catharina Hoock, Eileen Deuster, Wiebke Schaarschmidt, Adel Naimi, Dörthe Brüggmann, Frank Louwen, Kai Zacharowski, Jakob Thomas Busłowicz
article en

Abstract

Very high intraoperative oxytocin doses were not associated with reduced blood loss and were frequently administered in women at increased bleeding risk, suggesting confounding by indication. These results should therefore be regarded as hypothesis-generating rather than definitive evidence to guide prophylactic dosing.

Archives of Gynecology and ObstetricsVol. 313(1)
Goethe University Frankfurt (DE), University Hospital Frankfurt (DE)
Openalex Percentile: Top 4%
Maternal and fetal healthcare
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