Identification of IPF specific genes expressed by lung tissue-derived fibroblasts using next generation sequencing.
This transcriptomic analysis confirms ECM dysregulation as a core feature of IPF pathogenesis and highlights novel DEGs and hub genes with potential roles in fibrosis, providing a foundation for future functional and translational studies.
Authors
- Seung-lee Park (ORCID: https://orcid.org/0000-0002-1562-732X)
- Hun Soo Chang (ORCID: https://orcid.org/0000-0002-4025-4182)
- Hun-Gyu Hwang (ORCID: https://orcid.org/0000-0001-9304-7219)
- Jongin Lee (ORCID: https://orcid.org/0000-0003-4337-8444)
- Minkyung Kim (ORCID: https://orcid.org/0000-0002-2135-4305)
- Jung-Hyun Kim (ORCID: https://orcid.org/0000-0003-0719-3266)
- Jae-Sung Choi
- Choon-Sik Park
- Eun-Jeong Seo
Institutions
- Soonchunhyang University (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Bucheon University (KR)
Publication Details
- Journal
- PubMed
- Published
- 2026-03-27
- DOI
- https://doi.org/10.36141/svdld.2026.17698
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00