Elevating the standards of hypofibrinogenemia in trauma: Higher thresholds of admission fibrinogen predict mortality and organ dysfunction

Admission hypofibrinogenemia <200 mg/dL is associated with 28-day and 24 h mortality in trauma patients. Admission fibrinogen is also a marker for post-traumatic AKI and ARDS.

Authors

Deborah Michelle Stein (ORCID: https://orcid.org/0000-0003-3683-3963)
Justin E. Richards (ORCID: https://orcid.org/0000-0001-9656-2689)
Mary E. Burgoyne (ORCID: https://orcid.org/0000-0002-0969-4147)
Joseph A. Kufera
Rosemary Kozar

Institutions

University of Maryland, Baltimore (US)
University of Maryland Medical Center (US)
International Trauma Anesthesia and Critical Care Society (US)

Publication Details

Journal: Transfusion
Published: 2026-03-28
DOI: https://doi.org/10.1111/trf.70200
Primary Topic: Trauma, Hemostasis, Coagulopathy, Resuscitation
Type: article
Field-Weighted Citation Impact: 0.00

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article

Elevating the standards of hypofibrinogenemia in trauma: Higher thresholds of admission fibrinogen predict mortality and organ dysfunction

Deborah Michelle Stein, Justin E. Richards, Mary E. Burgoyne, Joseph A. Kufera et al.

Mar 28, 2026

Transfusion

Trauma, Hemostasis, Coagulopathy, Resuscitation

article

Elevating the standards of hypofibrinogenemia in trauma: Higher thresholds of admission fibrinogen predict mortality and organ dysfunction

Deborah Michelle Stein, Justin E. Richards, Mary E. Burgoyne, Joseph A. Kufera, Rosemary Kozar

March 28, 2026article en

Abstract

Admission hypofibrinogenemia <200 mg/dL is associated with 28-day and 24 h mortality in trauma patients. Admission fibrinogen is also a marker for post-traumatic AKI and ARDS.

Transfusion

University of Maryland, Baltimore (US), University of Maryland Medical Center (US), International Trauma Anesthesia and Critical Care Society (US)

Good health and well-being

Openalex Percentile: Top 3%

Trauma, Hemostasis, Coagulopathy, Resuscitation

DOI Source OpenAlex

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