Validating the 2022 <scp>WHO</scp> classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance

The 2022 WHO classification improves RAIR disease prediction, notably by recognizing high-grade carcinomas as a distinct entity. High-grade factors, especially tumour necrosis, which emerges as a key predictive factor, should be systematically reported in thyroid carcinoma pathology reports to enhance patient management and follow-up.

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Publication Details

Journal
Histopathology
Published
2026-03-28
DOI
https://doi.org/10.1111/his.70148
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Validating the 2022 WHO classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance

Mirela Diana Ilie, Myriam Decaussin‐Petrucci, C. Bournaud, L. Mebarki et al.
Histopathology
Thyroid Cancer Diagnosis and Treatment
article

Validating the 2022 WHO classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance

Mirela Diana Ilie, Myriam Decaussin‐Petrucci, C. Bournaud, L. Mebarki, Françoise Descôtes, Mireille Bertholon‐Grégoire, Hélène Lasolle, Fabien Subtil, Elise André, Jean‐Christophe Lifante, Françoise Borson‐Chazot
article en

Abstract

The 2022 WHO classification improves RAIR disease prediction, notably by recognizing high-grade carcinomas as a distinct entity. High-grade factors, especially tumour necrosis, which emerges as a key predictive factor, should be systematically reported in thyroid carcinoma pathology reports to enhance patient management and follow-up.

Histopathology
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Communauté urbaine de Lyon (FR), Hospices Civils de Lyon (FR), Hôpital Jeanne de Flandre (FR), Hôpital Lyon Sud (FR), Centre de Recherche en Cancérologie de Lyon (FR), Laboratoire de Biométrie et Biologie Evolutive (FR)
Good health and well-being
Openalex Percentile: Top 4%
Thyroid Cancer Diagnosis and Treatment
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Validating the 2022 <scp>WHO</scp> classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance — Mirela Diana Ilie, Myriam Decaussin‐Petrucci, et al. · Histopathology (2026) | TGRS Research Map | TGRS