Outcomes of hyperglycaemia in pregnancy in Africa: Systematic review and meta-analysis
The prevalence of adverse outcomes of HIP in Africa is high, in particular CS, preterm delivery and neonatal hypoglycaemia, with higher frequencies in pregestational T1DM and T2DM compared to GDM. Additionally, T2DM prevalence in women post-GDM is about 50%. The outcome data predominantly come from a few studies, indicating the necessity for more high-quality research to improve HIP-related maternal and child health in Africa. The high heterogeneity across most outcomes suggests that their prevalence varies across populations and underscores the need for more high-quality data. PROSPERO Registration Number: CRD42020184573.
Authors
- Veronique Nicolaou (ORCID: https://orcid.org/0000-0002-4895-6752)
- Mushi J. Matjila (ORCID: https://orcid.org/0000-0002-3796-1791)
- Mahmoud Werfalli (ORCID: https://orcid.org/0000-0002-5418-4138)
- Larske Marit Soepnel (ORCID: https://orcid.org/0000-0002-0076-7477)
- Naomi Levitt (ORCID: https://orcid.org/0000-0001-6480-8066)
- Tawanda Chivese
- Shane A. Norris
- Ezekiel Musa
Institutions
- South African Medical Research Council (ZA)
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Kaduna State University (NG)
- University of Benghazi (LY)
- North Cumbria Integrated Care NHS Foundation Trust (GB)
- South African Tuberculosis Vaccine Initiative (ZA)
- University of Washington Tacoma (US)
- University of Southampton (GB)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1371/journal.pone.0345743
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00