Post‐Neoadjuvant Chemotherapy Axillary Ultrasound in <scp>cN</scp> + Breast Cancer: Can It Reliably Support de‐Escalation of Axillary Surgery?

AUS following NAC provides only moderate accuracy, with a clinically relevant risk in patients lacking breast response. AUS alone should not determine omission of axillary surgery. A multimodal, biology-informed strategy combining AUS with other imaging techniques is needed to safely guide axillary de-escalation and minimize both overtreatment and undertreatment.

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Publication Details

Journal
Cancer Medicine
Published
2026-03-27
DOI
https://doi.org/10.1002/cam4.71759
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Post‐Neoadjuvant Chemotherapy Axillary Ultrasound in cN + Breast Cancer: Can It Reliably Support de‐Escalation of Axillary Surgery?

Marta Truffi, Daniela Bossi, F Corsi, Valentina Zanella et al.
Cancer Medicine
Breast Cancer Treatment Studies
article

Post‐Neoadjuvant Chemotherapy Axillary Ultrasound in cN + Breast Cancer: Can It Reliably Support de‐Escalation of Axillary Surgery?

Marta Truffi, Daniela Bossi, F Corsi, Valentina Zanella, Camilla Rossetti, Serena Mazzucchelli, Carlo Morasso, Roberta Brancaccio, Matilde Pelizzola, Sara Albasini, Elena Orvieto, Arianna Bonizzi
article en

Abstract

AUS following NAC provides only moderate accuracy, with a clinically relevant risk in patients lacking breast response. AUS alone should not determine omission of axillary surgery. A multimodal, biology-informed strategy combining AUS with other imaging techniques is needed to safely guide axillary de-escalation and minimize both overtreatment and undertreatment.

Cancer MedicineVol. 15(4)
University of Milan (IT), Istituti Clinici Scientifici Maugeri (IT)
Good health and well-being
Openalex Percentile: Top 4%
Breast Cancer Treatment Studies
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