Transvitreal Fibrinoid Syndrome Resulting in a Tractional Retinal Detachment Treated with Intravitreal tPA: A Case Report

This case highlights the efficacy of tPA use in fibrinoid syndrome when refractory to corticosteroids. tPA was able to manage this complication quickly and non-surgically in the setting of severe pre-retinal membrane formation and potential for rapid formation of TRD.

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Publication Details

Journal
Retinal Cases & Brief Reports
Published
2026-03-27
DOI
https://doi.org/10.1097/icb.0000000000001900
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
0.00
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article

Transvitreal Fibrinoid Syndrome Resulting in a Tractional Retinal Detachment Treated with Intravitreal tPA: A Case Report

David M. Skale, J. Youn, Alyssa Chung MPAS
Retinal Cases & Brief Reports
Retinal and Macular Surgery
article

Transvitreal Fibrinoid Syndrome Resulting in a Tractional Retinal Detachment Treated with Intravitreal tPA: A Case Report

David M. Skale, J. Youn, Alyssa Chung MPAS
article en

Abstract

This case highlights the efficacy of tPA use in fibrinoid syndrome when refractory to corticosteroids. tPA was able to manage this complication quickly and non-surgically in the setting of severe pre-retinal membrane formation and potential for rapid formation of TRD.

Retinal Cases & Brief Reports
Loma Linda University Medical Center (US), Apple (Israel) (IL), Loma Linda University (US)
Good health and well-being
Openalex Percentile: Top 4%
Retinal and Macular Surgery
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