Harms and benefits of discussing the brain disease model of addiction in therapeutic settings

Discussion of the brain disease model of addiction in clinical settings could harm or benefit the expectations held by treatment-engaged persons who use drugs (PWUD) regarding their therapeutic outcomes, but no study has experimentally tested this. Thirty-four PWUD who were engaged with Waythrough drug and alcohol recovery services were interviewed. Utilising methods from consumer psychology, PWUD were asked to imagine the brain disease and social stress models of addiction being discussed in two hypothetical therapist led support groups (in counterbalanced order within-subjects) and rate the therapeutic outcomes they expected would arise from each group. Participants agreed less with the brain disease model (d=0.37) and expected its discussion would reduce their likelihood of recovery (d=0.57), their therapeutic alliance with the facilitator and group peers (d=0.43), and self-blame for their addiction (d=0.40), compared to if the social stress model was discussed. Differences between conditions in expected quitting effort (d=0.29), adaptive coping (d=0.28), and negative self-perception (d=0.05) were not statistically significant. Treatment-engaged PWUD expected that discussion of the brain disease model of addiction in a hypothetical support group, compared to the social stress model, would harm their recovery chances and therapeutic alliance but benefit them by reducing self-blame for their addiction. Numeric effects on quitting effort and adaptive coping need replication with a larger sample. The null effect on negative self-perception informs theories of self-stigma. The study provokes reflection on how scientific addiction models are incorporated into clinical discourse to maximise clients’ recovery capital and avoid inadvertent epistemic harms. • The study supported the mixed-blessings model of addiction science communication. • Brain disease discourse modified the recovery capital of persons who use drugs. • Expected recovery and therapeutic alliance was harmed. • Self-blame for addiction was benefited. • There are implications for clinical discourse around addiction aetiology.

Authors

Institutions

Publication Details

Journal
Drug and Alcohol Dependence
Published
2026-03-01
DOI
https://doi.org/10.1016/j.drugalcdep.2026.113145
Primary Topic
Neuroethics, Human Enhancement, Biomedical Innovations
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Harms and benefits of discussing the brain disease model of addiction in therapeutic settings

Lee Hogarth, Charlie Oldfield, Daniel Casey, Mark Crowe
Drug and Alcohol Dependence
Neuroethics, Human Enhancement, Biomedical Innovations
article

Harms and benefits of discussing the brain disease model of addiction in therapeutic settings

Lee Hogarth, Charlie Oldfield, Daniel Casey, Mark Crowe
article en

Abstract

Discussion of the brain disease model of addiction in clinical settings could harm or benefit the expectations held by treatment-engaged persons who use drugs (PWUD) regarding their therapeutic outcomes, but no study has experimentally tested this. Thirty-four PWUD who were engaged with Waythrough drug and alcohol recovery services were interviewed. Utilising methods from consumer psychology, PWUD were asked to imagine the brain disease and social stress models of addiction being discussed in two hypothetical therapist led support groups (in counterbalanced order within-subjects) and rate the therapeutic outcomes they expected would arise from each group. Participants agreed less with the brain disease model (d=0.37) and expected its discussion would reduce their likelihood of recovery (d=0.57), their therapeutic alliance with the facilitator and group peers (d=0.43), and self-blame for their addiction (d=0.40), compared to if the social stress model was discussed. Differences between conditions in expected quitting effort (d=0.29), adaptive coping (d=0.28), and negative self-perception (d=0.05) were not statistically significant. Treatment-engaged PWUD expected that discussion of the brain disease model of addiction in a hypothetical support group, compared to the social stress model, would harm their recovery chances and therapeutic alliance but benefit them by reducing self-blame for their addiction. Numeric effects on quitting effort and adaptive coping need replication with a larger sample. The null effect on negative self-perception informs theories of self-stigma. The study provokes reflection on how scientific addiction models are incorporated into clinical discourse to maximise clients’ recovery capital and avoid inadvertent epistemic harms. • The study supported the mixed-blessings model of addiction science communication. • Brain disease discourse modified the recovery capital of persons who use drugs. • Expected recovery and therapeutic alliance was harmed. • Self-blame for addiction was benefited. • There are implications for clinical discourse around addiction aetiology.

Drug and Alcohol Dependence
University of Exeter (GB), University Hospital of North Durham (GB)
Good health and well-being
Openalex Percentile: Top 7%
Neuroethics, Human Enhancement, Biomedical Innovations
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.