Diagnostic and prognostic performance of circulating biomarkers in ovarian cancer

Introduction: Ovarian cancer is a leading cause of gynaecological cancer mortality. Ca125, the most widely used serum biomarker, has limited sensitivity for early-stage and type I tumours, prompting evaluation of additional blood-based markers. This umbrella review assesses the diagnostic and prognostic performance of serum and blood biomarkers in ovarian cancer.

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Publication Details

Journal
Academia oncology.
Published
2026-03-27
DOI
https://doi.org/10.20935/acadonco8189
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic and prognostic performance of circulating biomarkers in ovarian cancer

Georgia Zachou, A. Michael, Rui Wu
Academia oncology.
Ovarian cancer diagnosis and treatment
article

Diagnostic and prognostic performance of circulating biomarkers in ovarian cancer

Georgia Zachou, A. Michael, Rui Wu
article en

Abstract

Introduction: Ovarian cancer is a leading cause of gynaecological cancer mortality. Ca125, the most widely used serum biomarker, has limited sensitivity for early-stage and type I tumours, prompting evaluation of additional blood-based markers. This umbrella review assesses the diagnostic and prognostic performance of serum and blood biomarkers in ovarian cancer.

Academia oncology.Vol. 3(1)
Royal College of Surgeons of England (GB), Royal Surrey County Hospital (GB), University of Surrey (GB), London School of Hygiene & Tropical Medicine (GB), Royal Surrey NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 4%
Ovarian cancer diagnosis and treatment
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