Therapeutic potential of interleukin-33 blockade in mitigating synovial inflammation and cartilage damage

IL-33 blockade effectively mitigates synovial inflammation and joint destruction by suppressing the proliferation, migration, and invasion of RA-FLSs while promoting their apoptosis. Targeting IL-33 may represent a promising strategy for the treatment of rheumatoid arthritis.

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Publication Details

Journal
Scandinavian Journal of Rheumatology
Published
2026-03-27
DOI
https://doi.org/10.1080/03009742.2026.2640725
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic potential of interleukin-33 blockade in mitigating synovial inflammation and cartilage damage

Yan Feng, S Wu, X Liu, Y Jiang et al.
Scandinavian Journal of Rheumatology
IL-33, ST2, and ILC Pathways
article

Therapeutic potential of interleukin-33 blockade in mitigating synovial inflammation and cartilage damage

Yan Feng, S Wu, X Liu, Y Jiang, D Li
article en

Abstract

IL-33 blockade effectively mitigates synovial inflammation and joint destruction by suppressing the proliferation, migration, and invasion of RA-FLSs while promoting their apoptosis. Targeting IL-33 may represent a promising strategy for the treatment of rheumatoid arthritis.

Scandinavian Journal of Rheumatology
Liaoning Vocational College of Medical (CN), Jinzhou Medical University (CN)
Openalex Percentile: Top 5%
IL-33, ST2, and ILC Pathways
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