Association between plasma concentrations of integrase strand transfer inhibitors and body weight gain in women living with HIV

Higher RAL plasma concentrations were only modestly associated with percent body weight gain in WWH, unlike DTG or EVG. These findings do not suggest a consistent exposure-response relationship between INSTI concentrations and weight gain.

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Publication Details

Journal
AIDS
Published
2026-03-26
DOI
https://doi.org/10.1097/qad.0000000000004496
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between plasma concentrations of integrase strand transfer inhibitors and body weight gain in women living with HIV

Jennifer Cocohoba, Cecile Delille Lahiri, Julie B. Dumond, Joffi Musonge-Effoe et al.
AIDS
HIV-related health complications and treatments
article

Association between plasma concentrations of integrase strand transfer inhibitors and body weight gain in women living with HIV

Jennifer Cocohoba, Cecile Delille Lahiri, Julie B. Dumond, Joffi Musonge-Effoe, C. Christina Mehta, Adrian Khoei, Jessica A. Alvarez, Adaiah P. Soibi-Harry, Leah H. Rubin, C Sykes, I. Ofotokun, Mattie Hartauer, Elizabeth Topper, Maria L. Alcaide, Anjali Sharma, Audrey L. French, Phyllis C. Tien, Michelle Floris-Moore, Seble Kassaye, Anandi N. Sheth, Deborah Konkle-Parker, Michael Augenbraun, Qian Yang
article en

Abstract

Higher RAL plasma concentrations were only modestly associated with percent body weight gain in WWH, unlike DTG or EVG. These findings do not suggest a consistent exposure-response relationship between INSTI concentrations and weight gain.

AIDS
University of North Carolina at Chapel Hill (US), Albert Einstein College of Medicine (US), Johns Hopkins University (US), University of Miami (US), Emory University (US), University of California, San Francisco (US), SUNY Downstate Health Sciences University (US), Georgetown University (US), Johns Hopkins Medicine (US), Georgetown University Medical Center (US), John H. Stroger, Jr. Hospital of Cook County (US), University of Mississippi Medical Center (US), Zero to Three (US)
Gender equality
Openalex Percentile: Top 5%
HIV-related health complications and treatments
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