PKF118-310 as a Potential Small Molecule Inhibitor Targeting the Wnt/β-Catenin Pathway for Gastric Cancer Therapy
PKF118-310 exhibits potent anti-tumor effects in GC by inhibiting the Wnt/β-catenin signaling pathway, reducing tumor growth, and targeting CSCs. These findings suggest PKF118-310 as a promising therapeutic candidate for GC treatment.
Authors
- Yung‐Yu Hsieh (ORCID: https://orcid.org/0000-0001-8465-5204)
- Te‐Sheng Chang (ORCID: https://orcid.org/0000-0002-4205-2912)
- Chung‐Kuang Lu (ORCID: https://orcid.org/0000-0002-3688-5002)
- Chin Li (ORCID: https://orcid.org/0000-0002-5457-9623)
- Ming‐Ko Chiang (ORCID: https://orcid.org/0000-0002-4849-0534)
- Wei‐Ming Chen (ORCID: https://orcid.org/0000-0002-4949-393X)
- KUO-LIANG WEI
Institutions
- National Sun Yat-sen University (TW)
- National Chung Cheng University (TW)
- Chang Gung University (TW)
- Chiayi Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Anticancer Research
- Published
- 2026-03-27
- DOI
- https://doi.org/10.21873/anticanres.18084
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00