Survival and prognostic factors of anaplastic hemangiopericytoma/solitary fibrous tumor grade III

In this NCDB cohort of intracranial grade III SFT/HPC, improved overall survival was associated with younger age, private insurance status, and treatment with surgery alone or surgery combined with radiation therapy. Chemotherapy was not associated with a survival benefit. Interpretation of treatment effects should be cautious, given the potential for selection bias in chemotherapy utilization and the risk of immortal time bias analyses of radiotherapy. Continued advances in therapeutic strategies are needed to further improve survival in this rare and clinically devastating disease.

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Publication Details

Journal
Acta Neurochirurgica
Published
2026-03-27
DOI
https://doi.org/10.1007/s00701-026-06843-1
Primary Topic
Soft tissue tumor case studies
Type
article
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article

Survival and prognostic factors of anaplastic hemangiopericytoma/solitary fibrous tumor grade III

Daniel Valdivia, Cynthia T. Daut, Aman M. Patel, Amar D. Desai et al.
Acta Neurochirurgica
Soft tissue tumor case studies
article

Survival and prognostic factors of anaplastic hemangiopericytoma/solitary fibrous tumor grade III

Daniel Valdivia, Cynthia T. Daut, Aman M. Patel, Amar D. Desai, Vraj K Shah, Jean Anderson Eloy, Prayag Patel, Jonathan H. Sherman, James K. Liu, Alejandro Pando, Yaxel Levin-Carrion
article en

Abstract

In this NCDB cohort of intracranial grade III SFT/HPC, improved overall survival was associated with younger age, private insurance status, and treatment with surgery alone or surgery combined with radiation therapy. Chemotherapy was not associated with a survival benefit. Interpretation of treatment effects should be cautious, given the potential for selection bias in chemotherapy utilization and the risk of immortal time bias analyses of radiotherapy. Continued advances in therapeutic strategies are needed to further improve survival in this rare and clinically devastating disease.

Acta NeurochirurgicaVol. 168(1)
Rutgers, The State University of New Jersey (US), Northwestern University (US), Saint Barnabas Medical Center (US), Johnson University (US), Neurosurgeons of New Jersey (US), Neurological Surgery (US), Rutgers New Jersey Medical School (US)
Openalex Percentile: Top 4%
Soft tissue tumor case studies
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