<i>TFE3</i> -rearranged PEComa-like neoplasm harboring a novel <i>ZBED6::TFE3</i> fusion with an unusual immunophenotype
Based on a literature search of PubMed using the terms "PEComa", "PEComa-like", and "TFE3", this is the first case of a TFE3-rearranged PEComa-like neoplasm with ZBED6::TFE3 fusion, along with unusual morphologic and immunohistochemical phenotypes. The identification of the current case further expands the pathologic and genetic spectrum of this rare entity, highlighting the importance of integrating morphologic, immunohistochemical, and molecular findings in such cases.
Authors
- Xia He (ORCID: https://orcid.org/0000-0002-7314-1002)
- Hongying Zhang (ORCID: https://orcid.org/0000-0003-4748-4121)
- Ran Peng (ORCID: https://orcid.org/0000-0002-3799-9677)
- Wenyi Jing
- Lijuan Cui
- Min Chen
- Yue Wu
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Suizhou Central Hospital (CN)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1093/ajcp/aqag017
- Primary Topic
- Tuberous Sclerosis Complex Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00