Tenascin-C and Fibrosis as Prognostic Predictors of Peripartum Cardiomyopathy ― A Histopathological Study ―
Background: Peripartum cardiomyopathy (PPCM) is a potentially life-threatening condition. The histological characteristics of PPCM as risk factors for poor outcomes have not been thoroughly investigated. This study evaluated the pathological findings of PPCM, with a particular focus on inflammatory factors such as tenascin-C (TNC) and interleukin-6, which may predict left ventricular dysfunction and the prognosis of PPCM.
Authors
- Hatsue Ishibashi-Ueda
- Yasumasa Tsukamoto (ORCID: https://orcid.org/0000-0002-0963-6940)
- Kinta Hatakeyama (ORCID: https://orcid.org/0000-0001-7729-1836)
- Kisaki Amemiya (ORCID: https://orcid.org/0000-0001-7912-7423)
- Yoshihiko Ikeda (ORCID: https://orcid.org/0000-0001-6395-5072)
- Yoshiaki Morita (ORCID: https://orcid.org/0000-0003-4758-2311)
- Keiko Ohta-Ogo
- Chizuko Aoki-Kamiya
- Junko Nakashima
- Manabu Matsumoto
- Jun Yoshimatsu
Institutions
- Chikamori Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1253/circj.cj-25-0768
- Primary Topic
- Cardiovascular Issues in Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00