Molluscum Contagiosum Complicated With an Epidermal Cyst: A Case Report

ABSTRACT Molluscum contagiosum (MC) is a viral infection that primarily affects pediatric patients, sexually active young adults, and immunocompromised individuals of all ages. Clinically, MC presents as firm, rounded, pink, or skin‐colored papules with a shiny and umbilicated surface. Microscopic histological findings include a crateriform invagination of the hyperplastic epithelium composed of enlarged keratinocytes containing inclusion bodies known as Henderson–Patterson bodies. In some patients, including immunocompetent children, the morphology of MC lesions can vary. Giant MC lesions can mimic cysts, abscesses, or condylomas. Erosive MC lesions can mimic eczema vaccinatum. The papules may also be pearly white or reddish in color. Here, we report a case of a Molluscum contagiosum infection complicated by an epidermal cyst.

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Journal
Clinical Case Reports
Published
2026-03-26
DOI
https://doi.org/10.1002/ccr3.72291
Primary Topic
Poxvirus research and outbreaks
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article
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article

Molluscum Contagiosum Complicated With an Epidermal Cyst: A Case Report

Weian Kuang, Yun Zou, Na Qiao, Jiangtao Zheng et al.
Clinical Case Reports
Poxvirus research and outbreaks
article

Molluscum Contagiosum Complicated With an Epidermal Cyst: A Case Report

Weian Kuang, Yun Zou, Na Qiao, Jiangtao Zheng, Wenjin Geng, Xunguo Yin, Ruixian Niu
article en

Abstract

ABSTRACT Molluscum contagiosum (MC) is a viral infection that primarily affects pediatric patients, sexually active young adults, and immunocompromised individuals of all ages. Clinically, MC presents as firm, rounded, pink, or skin‐colored papules with a shiny and umbilicated surface. Microscopic histological findings include a crateriform invagination of the hyperplastic epithelium composed of enlarged keratinocytes containing inclusion bodies known as Henderson–Patterson bodies. In some patients, including immunocompetent children, the morphology of MC lesions can vary. Giant MC lesions can mimic cysts, abscesses, or condylomas. Erosive MC lesions can mimic eczema vaccinatum. The papules may also be pearly white or reddish in color. Here, we report a case of a Molluscum contagiosum infection complicated by an epidermal cyst.

Clinical Case ReportsVol. 14(4)
Qujing Normal University (CN)
Openalex Percentile: Top 15%
Poxvirus research and outbreaks
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Molluscum Contagiosum Complicated With an Epidermal Cyst: A Case Report — Weian Kuang, Yun Zou, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS