Association between Apolipoprotein B (ApoB) and suicidal ideation: a cross-sectional study and Mendelian randomization analysis
The present study found a significant positive association between serum ApoB levels and suicidal ideation, especially among smokers. MR analysis failed to provide causal evidence of ApoB on suicidal ideation. More research is needed to clarify the potential role of ApoB in the development of suicidal ideation.
Authors
- Changhao Fu (ORCID: https://orcid.org/0000-0001-7568-3369)
- Hongping Cheng
- Mixue Guo
- Hongli Wan
- Huqiang Dong (ORCID: https://orcid.org/0009-0005-3087-773X)
- Haifeng Zhang (ORCID: https://orcid.org/0000-0003-1938-3796)
- Xintian Cai
Institutions
- Hubei University of Medicine (CN)
- University of Electronic Science and Technology of China (CN)
- Jilin University (CN)
- Northwest University (CN)
- First Hospital of Jilin University (CN)
- Ningxia Medical University (CN)
- First Hospital of Xi'an (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Annals of General Psychiatry
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1186/s12991-026-00645-6
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00