Organophotoredox-Catalyzed Vinyl Group Transfer Reaction: An Introduction to 4-Vinyl-1,4-dihydropyridines
The visible-light-driven, organophotoredox-catalyzed vinyl group transfer reaction is described. The strategic use of proaromatic, bench-stable, and readily prepared 4-vinyl-dihydropyridine (DHP) derivatives triggers the vinyl group transfer that can couple stereoselectively with fluorinated esters and amides to forge the C(sp<sup>3</sup>)-C(sp<sup>2</sup>) bond. The obtained products are transformed into diverse fluorinated scaffolds. Preliminary mechanistic investigations are outlined.
Authors
- Sandeep Patel
- A. CHAKRABORTY (ORCID: https://orcid.org/0009-0008-4208-6339)
- Suryansh Singh Aristha
- Indranil Chatterjee
- Akshay Kumar Mandhotra
Institutions
- Indian Institute of Technology Ropar (IN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1021/acs.orglett.6c00693
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00