Visible-Light-Driven Radical Cascade Cyclization of 4-(N-Alkyl-Nacrylamido)coumarins: Access to Difluoroalkylated 4,5-Fused Coumarins and Coumarin[4,3-b]pyridinones
An efficient and practical visible-light-driven cascade difluoroalkylation/cyclization of 4-( N -alkyl- N -acrylamido)coumarins has been developed using readily accessible bromodifluoromethylphosphonium bromide ([Ph 3 PCF 2 H] + Br - ) as a difluoromethyl radical precursor. This protocol enables the rapid construction of...
Authors
- Jinwei Yuan (ORCID: https://orcid.org/0000-0002-4170-4894)
- Yongmei Xiao (ORCID: https://orcid.org/0000-0002-8573-4171)
- Donghui Wei
- Meng Yan
- Shi-Long Zhang
- Xin-Ya Wang
- Lingbo Qu
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d6qo00192k
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00