Epimorphic Regeneration of Mammalian Digit Tips

The article presents lecture materials on regeneration mechanisms from the textbook “Lectures on Regenerative Medicine.” An example of epimorphic regeneration in mammals is considered—the cellular mechanisms of tissue restoration of the digit tip after amputation. This model is a relevant object of research, since it allows us to study the mechanisms of both the formation of a specialized temporary structure called blastema and subsequent morphogenesis, which results in the full restoration of all amputated tissues.