Paired-sample Analysis of ERG Expression and TMPRSS2–ERG Fusion in Treatment-induced Neuroendocrine Prostate Cancer
This study highlights heterogeneity in TMPRSS2-ERG fusion dynamics during t-NEPC evolution and suggests a potential association between ERG expression and earlier NE differentiation. This study provides a rare opportunity to analyze paired pre- and post-NEPC tissues, offering valuable insight into the relationship between ERG and TMPRSS2-ERG fusion gene expression and clinical parameters.
Authors
- Kyo Inoue (ORCID: https://orcid.org/0000-0001-5847-1727)
- Tatsushi Kawada (ORCID: https://orcid.org/0000-0002-8369-9712)
- Satoshi Katayama (ORCID: https://orcid.org/0000-0002-8377-2457)
- Ryu Shigehisa (ORCID: https://orcid.org/0009-0005-3350-9123)
- Atsushi Takamoto (ORCID: https://orcid.org/0000-0002-1107-2291)
- Kenichi Nishimura
- Shinkuro Yamamoto (ORCID: https://orcid.org/0000-0002-3620-7666)
- T. Saika
- NORIYOSHI MIURA
- RYUTA WATANABE
- MOTOO ARAKI
Institutions
- Okayama University (JP)
- Fukuyama City Hospital (JP)
- Ehime University (JP)
- Kōchi University (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2026-03-27
- DOI
- https://doi.org/10.21873/anticanres.18085
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00