CORONATE: A Novel Questionnaire to Assess the Long-Term Impact of Psoriasis on Patients’ Lives

Introduction: Psoriasis has a profound impact on patients’ quality of life, affecting their emotional well-being, social interactions, and career choices. However, current assessment tools fail to capture the long-term burden of psoriasis. Objective: The aim of this study was to develop the CORONATE questionnaire, designed to assess the lifelong impact of moderate-to-severe psoriasis on patients' lives. Methods: A multicenter cross-sectional study was conducted in 15 Italian dermatology centers. This study included 300 patients (age ≥30 years) diagnosed with moderate-to-severe psoriasis (PASI ≥10 or PASI <10 with involvement of sensitive areas). The CORONATE questionnaire, initially consisting of 25 items, was refined through factor analysis. Exploratory and confirmatory factor analyses were performed. Results: The final questionnaire included 18 items grouped into two dimensions: "Work Issues" (5 items) and "Psychosocial Life" (13 items). Factor analysis confirmed strong internal consistency (Cronbach’s alpha: Work Issues = 0.81; Psychosocial Life = 0.91). The model showed excellent fit indices (χ² (153) = 6956.471, P<0.001; Comparative Fit Index = 0.998; Tucker-Lewis Index = 0.998; Standardized Root Mean Square Residual = 0.053). Conclusion: The CORONATE questionnaire is a reliable tool for assessing the cumulative burden of psoriasis. Its implementation in clinical practice may improve personalized patient care.

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Journal
Dermatology Practical & Conceptual
Published
2026-03-27
DOI
https://doi.org/10.5826/dpc.160a7073
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
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article

CORONATE: A Novel Questionnaire to Assess the Long-Term Impact of Psoriasis on Patients’ Lives

Simone Ribero, Lucia Peterle, P. Amerio, Maria Esposito et al.
Dermatology Practical & Conceptual
Psoriasis: Treatment and Pathogenesis
article

CORONATE: A Novel Questionnaire to Assess the Long-Term Impact of Psoriasis on Patients’ Lives

Simone Ribero, Lucia Peterle, P. Amerio, Maria Esposito, Giulia Nunziati, Anna Levi, Martina Accorinti, Christian Ciolfi, Anna Maria Offidani, Martina Burlando, Francesca Sampogna, A. Parodi, Alexandra MG Brunasso, Alessia Lozito, Gennaro Marco Falco, Sara Di Fino, Barbara Zucchi, Andrea Conti, Caterina Foti, Marina Venturini, Paolo Romita, Pietro Perini, Claudio Guarneri, Stefano Piaserico, Maria Concetta Fargnoli, Francesca Satolli, Paolo Gisondi, Daria Nucciarelli, Claudio Bonifati, Francesca Prignano, Marika Iarrera, Clara De Simone, Dario Graceffa, Francesco Loconsole
article en

Abstract

Introduction: Psoriasis has a profound impact on patients’ quality of life, affecting their emotional well-being, social interactions, and career choices. However, current assessment tools fail to capture the long-term burden of psoriasis. Objective: The aim of this study was to develop the CORONATE questionnaire, designed to assess the lifelong impact of moderate-to-severe psoriasis on patients' lives. Methods: A multicenter cross-sectional study was conducted in 15 Italian dermatology centers. This study included 300 patients (age ≥30 years) diagnosed with moderate-to-severe psoriasis (PASI ≥10 or PASI <10 with involvement of sensitive areas). The CORONATE questionnaire, initially consisting of 25 items, was refined through factor analysis. Exploratory and confirmatory factor analyses were performed. Results: The final questionnaire included 18 items grouped into two dimensions: "Work Issues" (5 items) and "Psychosocial Life" (13 items). Factor analysis confirmed strong internal consistency (Cronbach’s alpha: Work Issues = 0.81; Psychosocial Life = 0.91). The model showed excellent fit indices (χ² (153) = 6956.471, P<0.001; Comparative Fit Index = 0.998; Tucker-Lewis Index = 0.998; Standardized Root Mean Square Residual = 0.053). Conclusion: The CORONATE questionnaire is a reliable tool for assessing the cumulative burden of psoriasis. Its implementation in clinical practice may improve personalized patient care.

Dermatology Practical & ConceptualVol. 16
Università Cattolica del Sacro Cuore (IT), University of Messina (IT), University of Verona (IT), Marche Polytechnic University (IT), University of Parma (IT), University of Padua (IT), University of L'Aquila (IT), Agostino Gemelli University Polyclinic (IT), University of Chieti-Pescara (IT), Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Istituto Dermopatico dell'Immacolata (IT), Ospedale Infermi di Rimini (IT), San Gallicano Hospital (IT), Ospedale Policlinico San Martino (IT), University of the Sacred Heart (JP), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Villa Torri Hospital (IT), ABB (Italy) (IT), University of Florence (IT), University of Turin (IT), University of Bari Aldo Moro (IT), University of Brescia (IT)
Openalex Percentile: Top 5%
Psoriasis: Treatment and Pathogenesis
DOIOpen Access PDFOpenAlex
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