Design and implementation of a novel integrated timing and fast protection system for in-hospital AB-BNCT
Accelerator-based boron neutron capture therapy (AB-BNCT) necessitates highly reliable timing and rapid protection systems with minimal latency to ensure safe and synchronized operation. Conventional clinical accelerator control architectures; however, are often characterized by fragmented subsystems, excessive signal delays, and insufficient integration of timing, protection, and device control functions. To address these challenges, we introduce a unified hardware architecture specifically designed for AB-BNCT. This system integrates device control, timing, and fast protection into a single standardized platform using a custom reverse backplane that provides direct, low-latency data paths. Such a centralized design eliminates redundant interconnections, reduces end-to-end propagation delay, and enhances real-time responsiveness. Precise measurements indicate that the core protection logic responds in under 500 ns, excluding interlock-communication latency, thereby establishing a new benchmark for medical accelerator safety systems. Additionally, an intelligent beam-operation and shutdown mechanism is complemented to dynamically optimize beam delivery while ensuring fail-safe termination under fault conditions. This work offers three key contributions: First, it introduces the first integrated hardware platform tailored for AB-BNCT; second, it demonstrates record-low protection latency validated by metrology-grade testing; and last, it presents a safety-aware beam-control strategy that integrates real-time protection with clinical workflow stability. The proposed architecture significantly enhances the reliability, efficiency, and clinical feasibility of next-generation AB-BNCT facilities.
Authors
- Kangjia Xue (ORCID: https://orcid.org/0000-0002-9571-7981)
- D. P. Jin
- Zhiping Li (ORCID: https://orcid.org/0000-0001-7513-8272)
- Linyan Rong (ORCID: https://orcid.org/0000-0002-2195-2487)
- Xuan Wu (ORCID: https://orcid.org/0000-0003-1086-7890)
- Yongcheng He
- Peng Zhu
- Zhencheng Mu
- Huafu Ouyang
- Yuliang Zhang
- Mingtao Li
- Lin Wang
Institutions
- Chinese Academy of Sciences (CN)
- China Spallation Neutron Source (CN)
- Institute of High Energy Physics (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Nuclear Engineering and Technology
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1016/j.net.2026.104279
- Primary Topic
- Boron Compounds in Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00