Definite neuroborreliosis with atypical antibody-profiles: a case report
Our cases demonstrate that Lyme neuroborreliosis patients with symptom duration for several weeks and a well-functioning immune system can present with atypical antibody profiles. Consequently, we suggest that in cases with pleocytosis and symptoms compatible with Lyme neuroborreliosis but negative Borrelia burgdorferi antibody index, one should consider supplementary laboratory testing to confirm the diagnosis.
Authors
- Unn Ljøstad (ORCID: https://orcid.org/0000-0002-7666-1396)
- Åslaug Rudjord Lorentzen (ORCID: https://orcid.org/0000-0002-6918-4157)
- Åse Mygland (ORCID: https://orcid.org/0000-0001-9160-2805)
- Steffan D. Bos (ORCID: https://orcid.org/0000-0002-2975-7520)
- Ingerid Skarstein (ORCID: https://orcid.org/0009-0006-3221-3643)
- Hanne Quarsten (ORCID: https://orcid.org/0000-0001-6469-525X)
- Randi Eikeland (ORCID: https://orcid.org/0000-0003-0104-9626)
- Anne Marit Solheim (ORCID: https://orcid.org/0000-0001-7357-6287)
- Elling Ulvestad (ORCID: https://orcid.org/0000-0001-5901-8422)
- Harald Reiso (ORCID: https://orcid.org/0000-0003-4874-8707)
Institutions
- Norwegian Institute of Public Health (NO)
- University of Oslo (NO)
- University of Agder (NO)
- Haukeland University Hospital (NO)
- Hospital of Southern Norway (NO)
- Cancer Registry of Norway (NO)
- Sørlandet Sykehus (NO)
- University of Bergen (NO)
Publication Details
- Journal
- Journal of Medical Case Reports
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1186/s13256-026-05925-z
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00