Editorial Commentary

The editorial team welcomes you to the first issue of the year, the January–March issue of the Journal of Human Reproductive Sciences. As the journal grows with a wider reach and readership, we will continue to strive to publish good-quality scientific papers that help in improving clinical practice in the field of infertility. The current issue has more clinical studies with one review and nine original articles. The first review paper by Kushwaha A et al. is on the prevalence of infertility in South Asia and highlights the need for region-specific data. In a randomized controlled trial by Kumari A et al., an extended regimen of Letrozole was reported to result in better follicular response compared to the standard regimen while treating women with polycystic ovarian syndrome (PCOS) for infertility. In another trial, the investigators compared the effectiveness of different analgesic (Ketofol and Ketodex) regimens for achieving analgesia during transvaginal oocyte retrieval. In a retrospective cohort study, McClellan E et al. evaluated the impact of low-dose aspirin on frozen embryo transfer outcomes following transfer of euploid embryos. In an observational study by Vidua R et al., the survival of sperm following postmortem sperm retrieval was studied, which gave valuable insights into sperm recovery in these situations. In a prospective experimental study, the investigators explored the utility of adding plasma-rich growth factors during sperm cryopreservation to improve the post thaw recovery. In a cross-sectional study from a rural hospital, the authors reported psychosocial and economic factors affecting couples with infertility. A similar study compared the prevalence of depression, anxiety, stress, and fertility quality of life scores among women with PCOS versus those women without PCOS. In another large study, the authors explored the health-seeking behavior and the delay in care delivery in a sexual health clinic. Finally, a laboratory observational study explored the methylation patterns and epigenetic modifications in women with PCOS, helping in our understanding of its pathogenesis. As the new year starts, we look forward to publishing more clinical studies as well as high-quality systematic reviews in the field of Reproductive Medicine.