Disruption of the circadian rhythm induces acute pancreatitis via amino acid metabolism-mediated macrophage infiltration

Our study establishes a link between circadian disruption and an elevated risk of pancreatitis and suggests a potential therapeutic effect of melatonin treatment.

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Publication Details

Journal
Cellular and Molecular Gastroenterology and Hepatology
Published
2026-03-01
DOI
https://doi.org/10.1016/j.jcmgh.2026.101777
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Disruption of the circadian rhythm induces acute pancreatitis via amino acid metabolism-mediated macrophage infiltration

Yan Zhang, Wei Tong, Jianwei Zheng, Qi Wang et al.
Cellular and Molecular Gastroenterology and Hepatology
Pancreatitis Pathology and Treatment
article

Disruption of the circadian rhythm induces acute pancreatitis via amino acid metabolism-mediated macrophage infiltration

Yan Zhang, Wei Tong, Jianwei Zheng, Qi Wang, Siyang Ma, Jianbo Lv, Zhili He, Jian Wang, Weijian Liu, Haitao Li, Danyang Ling
article en

Abstract

Our study establishes a link between circadian disruption and an elevated risk of pancreatitis and suggests a potential therapeutic effect of melatonin treatment.

Cellular and Molecular Gastroenterology and Hepatology
Union Hospital (HK), Guiyang Medical University (CN), Wuhan University (CN), Affiliated Hospital of Guizhou Medical University (CN), Wuhan Union Hospital (CN), Fifth Hospital In Wuhan (CN), Central Hospital of Wuhan (CN), Tongji Hospital (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN), University of South China (CN)
Openalex Percentile: Top 4%
Pancreatitis Pathology and Treatment
DOIOpen Access PDFOpenAlex
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Disruption of the circadian rhythm induces acute pancreatitis via amino acid metabolism-mediated macrophage infiltration — Yan Zhang, Wei Tong, et al. · Cellular and Molecular Gastroenterology and Hepatology (2026) | TGRS Research Map | TGRS