Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Our data suggest that proactive TDM may offer clinical and pharmacokinetic benefits, particularly for paediatric IBD patients treated with IFX, while results for other outcomes and for ADL were less clear. Prospective studies are needed to confirm these findings and to further clarify the role of proactive TDM in this population.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-03-27
DOI
https://doi.org/10.1002/jpn3.70396
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Sebastian Stricker, Jan De Laffolie, Karlotta Pauline Hubert
Journal of Pediatric Gastroenterology and Nutrition
Inflammatory Bowel Disease
article

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Sebastian Stricker, Jan De Laffolie, Karlotta Pauline Hubert
article en

Abstract

Our data suggest that proactive TDM may offer clinical and pharmacokinetic benefits, particularly for paediatric IBD patients treated with IFX, while results for other outcomes and for ADL were less clear. Prospective studies are needed to confirm these findings and to further clarify the role of proactive TDM in this population.

Journal of Pediatric Gastroenterology and Nutrition
Justus-Liebig-Universität Gießen (DE)
Good health and well-being
Openalex Percentile: Top 5%
Inflammatory Bowel Disease
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