MIRF-Net: A Multimodal Data Fusion Framework for Intrapartum Fetal Risk Assessment

Accurate assessment of hypoxia-related fetal risk during labour is essential for improving perinatal outcomes while avoiding unnecessary operative interventions. Although deep learning has shown promise for automated fetal risk assessment, most existing approaches rely on cardiotocography (CTG) alone; CTG interpretation is known to suffer from a high false-positive rate and may not fully reflect fetal status without complementary clinical context. To address this limitation, we propose MIRF-Net, a multimodal intrapartum fetal risk assessment framework that jointly models (i) CTG time-series signals, (ii) Gramian Angular Difference Field (GADF) images that encode global correlation structure of fetal heart rate, and (iii) structured maternal metadata. MIRF-Net combines a PatchTST encoder for CTG, a pretrained ResNet101 for GADF images, and an autoencoder for maternal metadata and then performs cross-modal interaction learning with a fusion Transformer for final risk prediction. Using 552 eligible CTG recordings from the public CTU-UHB intrapartum database, which were split into training, validation, and test sets at a ratio of 6:2:2, MIRF-Net outperforms representative baselines on the test set, achieving a quality index (QI) of 74.76%, AUC of 0.7413, and Brier score of 0.2537, indicating improved discrimination and better-calibrated risk probabilities. Ablation studies further confirm the complementary contributions of each modality and show that Transformer-based fusion yields the most consistent overall gains. These results suggest that MIRF-Net provides reliable decision support for intelligent intrapartum monitoring.

Authors

Institutions

Publication Details

Journal
Bioengineering
Published
2026-03-27
DOI
https://doi.org/10.3390/bioengineering13040385
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

MIRF-Net: A Multimodal Data Fusion Framework for Intrapartum Fetal Risk Assessment

Ziduo Yang, Yaqi Liang, Yaosheng Lu, Jieyun Bai
Bioengineering
Neonatal and fetal brain pathology
article

MIRF-Net: A Multimodal Data Fusion Framework for Intrapartum Fetal Risk Assessment

Ziduo Yang, Yaqi Liang, Yaosheng Lu, Jieyun Bai
article en

Abstract

Accurate assessment of hypoxia-related fetal risk during labour is essential for improving perinatal outcomes while avoiding unnecessary operative interventions. Although deep learning has shown promise for automated fetal risk assessment, most existing approaches rely on cardiotocography (CTG) alone; CTG interpretation is known to suffer from a high false-positive rate and may not fully reflect fetal status without complementary clinical context. To address this limitation, we propose MIRF-Net, a multimodal intrapartum fetal risk assessment framework that jointly models (i) CTG time-series signals, (ii) Gramian Angular Difference Field (GADF) images that encode global correlation structure of fetal heart rate, and (iii) structured maternal metadata. MIRF-Net combines a PatchTST encoder for CTG, a pretrained ResNet101 for GADF images, and an autoencoder for maternal metadata and then performs cross-modal interaction learning with a fusion Transformer for final risk prediction. Using 552 eligible CTG recordings from the public CTU-UHB intrapartum database, which were split into training, validation, and test sets at a ratio of 6:2:2, MIRF-Net outperforms representative baselines on the test set, achieving a quality index (QI) of 74.76%, AUC of 0.7413, and Brier score of 0.2537, indicating improved discrimination and better-calibrated risk probabilities. Ablation studies further confirm the complementary contributions of each modality and show that Transformer-based fusion yields the most consistent overall gains. These results suggest that MIRF-Net provides reliable decision support for intelligent intrapartum monitoring.

BioengineeringVol. 13(4)
Jinan University (CN)
Gender equality
Openalex Percentile: Top 4%
Neonatal and fetal brain pathology
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.