Generation of Fibrin-Based Aortic Vessels with Layer-Specific Cell Architecture Under Pulsatile Perfusion in a Clinical Organ Care System
This approach may be considered a proof of concept and constitutes a first step toward the development of biometric and functional large-diameter vessel replacements.
Authors
- Florian Helms (ORCID: https://orcid.org/0000-0002-5788-974X)
- Patrick Stadler (ORCID: https://orcid.org/0000-0002-5224-1522)
- Hans‐Klaus Höffler
- Michael Pflaum (ORCID: https://orcid.org/0000-0002-4539-386X)
- Mathias Wilhelmi (ORCID: https://orcid.org/0000-0001-8607-8068)
- Melanie Klingenberg
- Imke Becker
- Clara-Sophie Glomb
- Celina Delia Käding
- Arjang Ruhparwar
Institutions
- Medizinische Hochschule Hannover (DE)
- St. Bernward Krankenhaus (DE)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1007/s10439-026-04087-9
- Primary Topic
- Electrospun Nanofibers in Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00