Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

MRTK carries a poor prognosis despite multimodal treatment. Histologic diagnosis may not be confirmed at presentation, and MRTK cannot be reliably distinguished from Wilms tumor on imaging alone. As overall survival is similar, the decision regarding surgical timing in locally advanced tumors should be individualized based on perceived resectability, balancing the risk of intraoperative complications against the possibility of tumor progression during neoadjuvant therapy.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-03-26
DOI
https://doi.org/10.1002/1545-5017.70296
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Alexandra Dimmer, Maya M. Hammoud, Bhargava Mullapudi, Catherine B. Beckhorn et al.
Pediatric Blood & Cancer
Chromatin Remodeling and Cancer
article

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Alexandra Dimmer, Maya M. Hammoud, Bhargava Mullapudi, Catherine B. Beckhorn, Joseph G. Brungardt, Brian T. Craig, Tamer A. Ahmed, Nelson Piché, Stephanie F. Polites, Kelsey Mello, David Hoyt, Anastasia M Kahan, Emily K. Myers, Erin G. Brown, Katlyn G. McKay, Kathleen Doyle, Shannon L. Castle, Lindsay J. Talbot, Michela Carter, Michael Stellon, Grace R. Thompson, Jacob B. Davidson, Barrie S. Rich, Joseph C. Fusco, Jonathan P. Roach, Joshua Short, Elisabeth T. Tracy, Devashish Joshi, David H. Rothstein, Danielle B. Cameron, Nicholas Glenn Cost, Zachary J. Kastenberg, Julia Debertin, Kiyanna Williams, Peter F. Ehrlich, Richard D. Glick, Barrett P. Cromeens, John Lundstedt, Christa N. Grant, Harold J. Leraas, Nathan Martchenke, Marcus M. Malek, Chloé Boehmer, Hau D. Le, Charles R. Marchese, Timothy B. Lautz, Jennifer H. Aldrink, Elizabeth Fialkowski, Brian A. Coakley, Natashia M. Seemann, Sindhu V. Mannava, Sara A. Mansfield, Claire A. Wilson, Robin T. Petroze, Hannah Rinehardt, Jennifer M Schuh, Eugene S. Kim, Amanda Jensen, Alyssa Stetson, Roshni Dasgupta, Annie Le‐Nguyen, A. Javier Lopez, Paige Abril, M. Pitonak, Shay Rajaval, Aaron Barkhordar, Merit Gorgy, Dave R Lal, Anghela Z. Paredes, Kathryn Fowler, Peter Mattei, Mary Austin, Nelly‐Ange T. Kontchou, Andrew M. Davidoff, Joseph T. Murphy, William G. Lee, Andrew J. Murphy
article en

Abstract

MRTK carries a poor prognosis despite multimodal treatment. Histologic diagnosis may not be confirmed at presentation, and MRTK cannot be reliably distinguished from Wilms tumor on imaging alone. As overall survival is similar, the decision regarding surgical timing in locally advanced tumors should be individualized based on perceived resectability, balancing the risk of intraoperative complications against the possibility of tumor progression during neoadjuvant therapy.

Pediatric Blood & Cancer
Children's Hospital of Wisconsin (US), Cedars-Sinai Medical Center (US), Cincinnati Children's Hospital Medical Center (US), Seattle Children's Hospital (US), Children's Medical Center (US), St. Jude Children's Research Hospital (US), Nationwide Children's Hospital (US), Westchester Medical Center (US), Primary Children's Hospital (US), Children's Mercy Hospital (US), Mayo Clinic (US), The University of Texas MD Anderson Cancer Center (US), Oregon Health & Science University (US), Duke University (US), University of Washington (US), SUNY Upstate Medical University (US), Medical College of Wisconsin (US), University of Michigan (US), London Health Sciences Centre (CA), Centre Hospitalier Universitaire Sainte-Justine (CA), Riley Hospital for Children (US), University of Florida (US), Massachusetts General Hospital (US), Children's Hospital Colorado (US), Children's Hospital Central California (US), Cohen Children's Medical Center (US), Lurie Children's Hospital (US), Duke Medical Center (US), Children's Hospital of Pittsburgh (US), Children's Minnesota (US), University of Wisconsin American Family Children's Hospital (US), Northwestern Medicine (US), Mercy Research (US), C. S. Mott Children's Hospital (US), UC Davis Children's Hospital (US), Indiana University School of Medicine, The Ohio State University (US), Indiana University – Purdue University Indianapolis (US), Université de Montréal (CA), University of California, Davis (US), The University of Texas Southwestern Medical Center (US), Vanderbilt University Medical Center (US), University of Colorado Denver (US), Icahn School of Medicine at Mount Sinai (US)
No poverty
Openalex Percentile: Top 6%
Chromatin Remodeling and Cancer
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