Histological architecture of the intersphincteric region of the anal canal: implications for the anatomical basis of anal fistula pathways
The intersphincteric region of the anal canal is a structurally complex and compartmentalized anatomical entity. Its heterogeneous histological architecture provides an anatomical substrate that may explain the initiation and directional spread of anal fistulas, including pathways described in classical fistula classifications.
Authors
- Keiichi Akita (ORCID: https://orcid.org/0000-0002-2927-2937)
- Satoru Muro (ORCID: https://orcid.org/0000-0002-4709-6359)
- Yasuo Nakajima
- Akimoto Nimura
Institutions
- Tokyo Medical and Dental University (JP)
- Doai Memorial Hospital (JP)
- Institute of Science Tokyo (JP)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1007/s00384-026-05123-9
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00