Patterns and Predictors of Urinary Continence Recovery After Extraperitoneal Single-Port Robot-Assisted Radical Prostatectomy

Background/Objectives: Urinary continence recovery after robot-assisted radical prostatectomy (RARP) follows a progressive trajectory that is often simplified into binary outcomes. Modeling continence recovery as an ordered process may better reflect post-operative functional patterns and identify clinically relevant predictors. Methods: We retrospectively analyzed 180 patients undergoing extraperitoneal single-port RARP. At 6 months, continence recovery was classified into three ordered categories: early continence, late continence, and persistent incontinence. Multivariable ordinal logistic regression was used to identify independent predictors of continence recovery. The primary model included nerve-sparing (NS) status, postoperative complications, age, and prostate volume. Sensitivity analyses were performed by sequentially replacing prostate volume with body mass index, surgical case number, or preoperative prostate-specific antigen (PSA). An interaction between NS and age group was also tested. Results: NS surgery was the factor most strongly associated with favorable continence recovery (p < 0.001), followed by absence of post-operative complications (p = 0.003). Younger age and larger prostate volume were also independently associated with improved continence recovery. Sensitivity analyses confirmed the robustness of the primary model, as replacement of prostate volume with body mass index, surgical case number, or PSA did not improve model performance and did not alter the effect of NS surgery. No significant interaction between NS and age group was observed. Conclusions: Continence recovery after extraperitoneal RARP is primarily associated with NS surgery and an uncomplicated post-operative course, with age and prostate volume providing additional refinement. Modeling continence as an ordinal outcome offers a clinically meaningful framework for evaluating functional recovery after prostatectomy.

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Journal
Journal of Clinical Medicine
Published
2026-03-27
DOI
https://doi.org/10.3390/jcm15072563
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Patterns and Predictors of Urinary Continence Recovery After Extraperitoneal Single-Port Robot-Assisted Radical Prostatectomy

Luca Morgantini, Marwan Alkassis, Lorenzo Santodirocco, Jinchun Qi et al.
Journal of Clinical Medicine
Prostate Cancer Diagnosis and Treatment
article

Patterns and Predictors of Urinary Continence Recovery After Extraperitoneal Single-Port Robot-Assisted Radical Prostatectomy

Luca Morgantini, Marwan Alkassis, Lorenzo Santodirocco, Jinchun Qi, Simone Crivellaro
article en

Abstract

Background/Objectives: Urinary continence recovery after robot-assisted radical prostatectomy (RARP) follows a progressive trajectory that is often simplified into binary outcomes. Modeling continence recovery as an ordered process may better reflect post-operative functional patterns and identify clinically relevant predictors. Methods: We retrospectively analyzed 180 patients undergoing extraperitoneal single-port RARP. At 6 months, continence recovery was classified into three ordered categories: early continence, late continence, and persistent incontinence. Multivariable ordinal logistic regression was used to identify independent predictors of continence recovery. The primary model included nerve-sparing (NS) status, postoperative complications, age, and prostate volume. Sensitivity analyses were performed by sequentially replacing prostate volume with body mass index, surgical case number, or preoperative prostate-specific antigen (PSA). An interaction between NS and age group was also tested. Results: NS surgery was the factor most strongly associated with favorable continence recovery (p < 0.001), followed by absence of post-operative complications (p = 0.003). Younger age and larger prostate volume were also independently associated with improved continence recovery. Sensitivity analyses confirmed the robustness of the primary model, as replacement of prostate volume with body mass index, surgical case number, or PSA did not improve model performance and did not alter the effect of NS surgery. No significant interaction between NS and age group was observed. Conclusions: Continence recovery after extraperitoneal RARP is primarily associated with NS surgery and an uncomplicated post-operative course, with age and prostate volume providing additional refinement. Modeling continence as an ordinal outcome offers a clinically meaningful framework for evaluating functional recovery after prostatectomy.

Journal of Clinical MedicineVol. 15(7)
Hebei Medical University (CN), Policlinico Umberto I (IT), University of Illinois Chicago (US), Second Hospital of Hebei Medical University (CN), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 5%
Prostate Cancer Diagnosis and Treatment
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