Comparative analysis of different modalities of radiotherapy in vestibular schwannoma: tumor control, symptom evolution, and toxicity profiles
Both SRS and NFSRT achieve excellent long-term tumor control with low severe toxicity. For NFSRT, normofractionated doses above 55 Gy did not improve efficacy and may increase the recurrence risk, supporting moderate-dose regimens (50-54 Gy). Symptom stabilization confirms the safety of SRT, though headache and vertigo remain relevant long-term issues. Careful dose selection, patient counseling, and rehabilitation are essential to optimize outcomes.
Authors
- Klemens Zink (ORCID: https://orcid.org/0000-0001-5785-4101)
- Daniel Habermehl (ORCID: https://orcid.org/0009-0007-7316-6422)
- Linda Agolli (ORCID: https://orcid.org/0000-0003-1534-4386)
- Sebastian Adeberg (ORCID: https://orcid.org/0000-0001-8463-514X)
- Christopher Nimsky (ORCID: https://orcid.org/0000-0002-8216-9410)
- M. Fischer
- Kerem Tuna Tas
- Edgar Smalec
- Fatima Frosan Sheikhzadeh
- Ahmed Gawish
- André Kemmling
- Phillipp Lishewski
Institutions
- Goethe University Frankfurt (DE)
- Philipps University of Marburg (DE)
- Universitätsklinikum Gießen und Marburg (DE)
- University Hospital Frankfurt (DE)
- Giessen School of Theology (DE)
- Technische Hochschule Mittelhessen (DE)
Publication Details
- Journal
- Strahlentherapie und Onkologie
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1007/s00066-026-02516-1
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00