Differential serum dynamics of apelin, elabela, and angiotensinogen in CKD and haemodialysis: insights into peptide modulation across the dialysis procedure

These findings highlight distinct, peptide-specific responses to HD and support a context-dependent interplay between uremic burden, peptide systems, and dialysis-induced shifts. Apelinergic and RAS peptides may represent promising biomarkers of intradialytic cardiovascular modulation. Further studies are warranted to explore their prognostic and therapeutic implications in CKD.

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Publication Details

Journal
Renal Failure
Published
2026-03-26
DOI
https://doi.org/10.1080/0886022x.2026.2646404
Primary Topic
Apelin-related biomedical research
Type
article
Field-Weighted Citation Impact
0.00
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article

Differential serum dynamics of apelin, elabela, and angiotensinogen in CKD and haemodialysis: insights into peptide modulation across the dialysis procedure

Mariusz Suwała, Marcin Lisak, Natalia Serwin, Bartosz Wojciuk et al.
Renal Failure
Apelin-related biomedical research
article

Differential serum dynamics of apelin, elabela, and angiotensinogen in CKD and haemodialysis: insights into peptide modulation across the dialysis procedure

Mariusz Suwała, Marcin Lisak, Natalia Serwin, Bartosz Wojciuk, Bartłomiej Grygorcewicz, Martyna Opara-Bajerowicz, Karol Serwin, Aleksandra Gomółka, Adrianna Jerzyk, Aleksandra Cader-Ptak, Mateusz Cejko, Elżbieta Cecerska-Heryć, Emilia Spajzer, Aleksandra Manelska, Paulina Woźniak, Kacper Ćwikła, Katarzyna Bąk, Barbara Dołęgowska, Magda Wiśniewska
article en

Abstract

These findings highlight distinct, peptide-specific responses to HD and support a context-dependent interplay between uremic burden, peptide systems, and dialysis-induced shifts. Apelinergic and RAS peptides may represent promising biomarkers of intradialytic cardiovascular modulation. Further studies are warranted to explore their prognostic and therapeutic implications in CKD.

Renal FailureVol. 48(1)
Pomeranian Medical University (PL)
Good health and well-being
Openalex Percentile: Top 5%
Apelin-related biomedical research
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